Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682581 | 0.80 | HTT (0.35) | HTTHHATKDM4EGAAHPGD | |
| SCHEMBL23611615 | 0.71 | CHRNB2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL23611617 | 0.70 | CHRNB2 (0.31) | — | |
| SCHEMBL9683449 | 0.69 | HHAT (0.30) | HHAT | |
| SCHEMBL9683465 | 0.67 | CARM1 (0.33) | KDM4E | |
| SCHEMBL9684243 | 0.67 | CHRM2 (0.37) | HTTGAAHPGDTDP1 | |
| SCHEMBL9683453 | 0.67 | OPRM1 (0.35) | HTT | |
| SCHEMBL9684557 | 0.66 | BCHE (0.33) | KDM4EGAA | |
| SCHEMBL9684281 | 0.66 | OPRM1 (0.37) | — | |
| SCHEMBL9684133 | 0.65 | CYP2D6 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475187-A1 | Naphthothiophenimines for treating neuronal disorders caused by ischemia | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5064831-A | N-methyl-d-aspartate receptor antagonist | BRISTOL-MYERS SQUIBB CO. (US) | 1991-11-12 | — | — | US | disclosed |