Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 12/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 12/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | THPO | P40225 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684632 | 0.92 | SLC6A2 (0.36) | HTR2AHRH1KDM4ETP53CHRM2 | |
| SCHEMBL9683453 | 0.80 | OPRM1 (0.35) | SLC6A2SLC6A3OPRM1 | |
| SCHEMBL9684167 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL9684133 | 0.77 | CYP2D6 (0.38) | HTR2AHRH1KDM4ETP53CHRM2 | |
| SCHEMBL9683338 | 0.77 | POLB (0.34) | KDM4ETP53CYP3A4CYP2D6MEN1 | |
| SCHEMBL9682581 | 0.74 | HTT (0.35) | KDM4ESLC6A2SLC6A3 | |
| SCHEMBL9684243 | 0.74 | CHRM2 (0.37) | TP53CHRM2HSD17B10KMT2ACHRM4 | |
| SCHEMBL9684281 | 0.73 | OPRM1 (0.37) | OPRM1SIGMAR1 | |
| SCHEMBL9684260 | 0.72 | DUT (0.33) | — | |
| SCHEMBL9682616 | 0.68 | KDM1A (0.46) | HTR2AHRH1DRD2ADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475187-A1 | Naphthothiophenimines for treating neuronal disorders caused by ischemia | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |