Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683449 | 0.92 | HHAT (0.30) | — | |
| SCHEMBL9682581 | 0.69 | HTT (0.35) | ACHEKDM4EGAA | |
| SCHEMBL9683323 | 0.66 | HTT (0.30) | KDM4EGAA | |
| SCHEMBL13370362 | 0.65 | BCHE (0.40) | BCHEACHESLC18A3SIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL23611559 | 0.64 | OPRM1 (0.39) | BCHEACHESLC18A3SIGMAR1OPRM1 | |
| SCHEMBL9684243 | 0.64 | CHRM2 (0.37) | SIGMAR1GAA | |
| SCHEMBL4458509 | 0.63 | CEL (0.35) | — | |
| Hydrochloric Acid SCHEMBL23611588 | 0.63 | OPRM1 (0.38) | BCHEACHESLC18A3SIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL23611632 | 0.63 | SIGMAR1 (0.37) | BCHEACHESLC18A3SIGMAR1OPRM1 | |
| SCHEMBL9684167 | 0.61 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475187-A1 | Naphthothiophenimines for treating neuronal disorders caused by ischemia | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |