Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735938 | 0.89 | AR (0.42) | ARKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL10406730 | 0.85 | NOTUM (0.43) | ARKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL10986755 | 0.82 | AR (0.46) | ARKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL10407413 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL10986984 | 0.80 | AR (0.43) | ARKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL10652687 | 0.80 | DRD2 (0.41) | ARSMN1; SMN2MEN1KMT2ADRD2 | |
| SCHEMBL9797233 | 0.78 | AR (0.49) | ARKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9681581 | 0.74 | HTR7 (0.42) | KDM4EALDH1A1MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL9659383 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL9362478 | 0.73 | KMT2A (0.42) | ARALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2237970-A | — | — | None | — | — | JP | disclosed |
| EP-0495981-A1 | 4-ETHYL-1-(3-TRIFLUOROMETHYLPHENYL)-2-PYRROLIDINONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |
| JP-H02237970-A | 4-ETHYL-1-(3-TRIFLUOROMETHYLPHENYL)-2-PYRROLIDINONE DERIVATIVE AND HERBICIDE CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT | MITSUI TOATSU CHEM INC | 1990-09-20 | — | — | JP | disclosed |