SCHEMBL9683906

SCHEMBL9683906

CC1(CC(=O)O)Sc2sc(S(N)(=O)=O)cc2NC1=O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 16/20 0.55
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682080 0.71 CA2 (1.00) CA2
SCHEMBL15413177 0.66 ALDH1A1 (1.00) ALDH1A1
SCHEMBL9682708 0.66 CA2 (0.81) CA2
SCHEMBL9654181 0.63 CA2 (0.40) CA2
SCHEMBL9740275 0.62 CA2 (0.58) CA2
SCHEMBL9682119 0.62 CA2 (1.00) CA2
SCHEMBL7525460 0.62 CA2 (1.00) CA2ALDH1A1
SCHEMBL9652934 0.61 CA2 (0.38) CA2
SCHEMBL9682131 0.59 CA2 (0.61) CA2
SCHEMBL9673758 0.59 CA2 (0.46) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0479480-A2 Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antiglaucoma agents MERCK & CO. INC. (US) 1992-04-08 EP disclosed
US-5093332-A SUBSTITUTED THIENO(2,3-B)(1,4)THIAZINE-6-SULFONAMIDES AS ANTIGLAUCOMA AGENTS MERCK & CO., INC. (US) 1992-03-03 US disclosed