SCHEMBL9740275

SCHEMBL9740275

CC(=O)OC1Sc2sc(S(N)(=O)=O)cc2NC1=O

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682708 0.73 CA2 (0.81) CA2
SCHEMBL9682080 0.73 CA2 (1.00) CA2
SCHEMBL7525460 0.69 CA2 (1.00) CA2
SCHEMBL9683906 0.62 CA2 (0.55) CA2
SCHEMBL9682119 0.62 CA2 (1.00) CA2
SCHEMBL9683126 0.61 CA2 (0.70) CA2
SCHEMBL6095759 0.60 POLB (0.42)
SCHEMBL1568140 0.60 POLB (0.42)
SCHEMBL9682131 0.59 CA2 (0.61) CA2
SCHEMBL9683786 0.59 CA2 (0.61) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093332-A SUBSTITUTED THIENO(2,3-B)(1,4)THIAZINE-6-SULFONAMIDES AS ANTIGLAUCOMA AGENTS MERCK & CO., INC. (US) 1992-03-03 US claimed