Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686751 | 0.91 | TRPA1 (0.61) | TRPA1PTPN11LMNAHTTKDM4E | |
| SCHEMBL9684409 | 0.89 | TRPA1 (0.59) | TRPA1PTPN11LMNAHTTKDM4E | |
| SCHEMBL9685091 | 0.89 | TRPA1 (0.59) | TRPA1PTPN11LMNAHTTKDM4E | |
| SCHEMBL9685139 | 0.83 | TRPA1 (0.56) | TRPA1PTPN11LMNAHTTMAPK1 | |
| SCHEMBL9686176 | 0.83 | TRPA1 (0.57) | TRPA1LMNAHTTKDM4EALOX15 | |
| SCHEMBL8809831 | 0.82 | TRPA1 (0.52) | TRPA1PTPN11LMNAHTTNPC1 | |
| SCHEMBL9686187 | 0.80 | TRPA1 (0.52) | TRPA1PTPN11LMNAHTTKDM4E | |
| SCHEMBL9685390 | 0.80 | TRPA1 (0.60) | TRPA1PTPN11LMNAHTTKDM4E | |
| SCHEMBL9685239 | 0.80 | TRPA1 (0.60) | TRPA1PTPN11LMNAHTTKDM4E | |
| SCHEMBL9686804 | 0.79 | TRPA1 (0.52) | TRPA1LMNAHTTMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188094-B1 | QUINAZOLINE DERIVATIVES AND ANTIHYPERTENSIVE PREPARATIONS CONTAINING SAME AS EFFECTIVE COMPONENTS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4734418-A | Quinazoline compounds and antihypertensives | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0188094-A2 | Quinazoline derivatives and antihypertensive preparations containing same as effective components | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-RE31975-E | UNSATURATED POLYESTER, UNSATURATED MONOMER, AND VINYL ESTER COPOLYMER | UNION CARBIDE CORP. (US) | 1985-08-27 | — | — | US | disclosed |
| US-4288571-A | Polyester compositions | UNION CARBIDE CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |