SCHEMBL9685247

SCHEMBL9685247

[c]1ccc(NCC2CO2)cc1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8981580 0.85 SMN1; SMN2 (0.42) NPC1RAB9ASMN1; SMN2ALDH1A1GLA
SCHEMBL23852179 0.85 KCNH3 (0.40) NPC1RAB9ASMN1; SMN2ALDH1A1GLA
SCHEMBL175818 0.79 NPC1 (0.56) NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL21401818 0.79 SMN1; SMN2 (0.39) NPC1RAB9ASMN1; SMN2ALDH1A1
Water SCHEMBL28325020 0.78 L3MBTL1 (0.40) NPC1RAB9ASMN1; SMN2ALDH1A1
Water SCHEMBL44003 0.77 NPC1 (0.35) NPC1RAB9ASMN1; SMN2
SCHEMBL7535852 0.76 LMNA (0.38) NPC1RAB9ASMN1; SMN2ALDH1A1GLA
SCHEMBL4271408 0.76 L3MBTL1 (0.41) NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11702489 0.76 RAB9A (0.37) NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL244947 0.76 MAPT (0.50) NPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156957-B Water-based epoxy curing agent and preparation method and application thereof 上海骁鹏新材料科技有限公司 2020-11-17 CN claimed
CN-110156957-A Aqueous epoxy curing agent and its preparation method and application 上海骁鹏新材料科技有限公司 2019-08-23 CN claimed
CN-1816547-A Oxazolidinone antibiotics and derivatives thereof MERCK & CO INC (US) 2006-08-09 CN claimed
CN-1816534-A Oxazolidinone antibiotics and derivatives thereof MERCK & CO INC (US) 2006-08-09 CN claimed
CN-1816545-A Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof MERCK & CO INC (US) 2006-08-09 CN claimed
CN-105452349-B Nanocomposites comprising silica nanoparticles and dispersants, composites, articles, and methods of making the same 3M创新有限公司 2022-09-27 CN disclosed
CN-109890750-B Curable resins comprising nanoparticles containing surface-bonded hydrophobically modified alkyl groups 3M创新有限公司 2022-05-10 CN disclosed
CN-113646398-A Structural adhesive tape with epoxide microcapsules 3M创新有限公司 2021-11-12 CN disclosed
CN-113613775-A Epoxide microcapsules with pickering emulsifiers 3M创新有限公司 2021-11-05 CN disclosed
CN-107735427-B Ammonium salt catalyzed benzoxazine polymerization 3M创新有限公司 2021-06-04 CN disclosed
CN-110156957-B Water-based epoxy curing agent and preparation method and application thereof 上海骁鹏新材料科技有限公司 2020-11-17 CN disclosed
CN-110156957-A Aqueous epoxy curing agent and its preparation method and application 上海骁鹏新材料科技有限公司 2019-08-23 CN disclosed
CN-107112221-A Dicing tape 电化株式会社 2017-08-29 CN disclosed
CN-1816534-A Oxazolidinone antibiotics and derivatives thereof MERCK & CO INC (US) 2006-08-09 CN disclosed
CN-1816545-A Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof MERCK & CO INC (US) 2006-08-09 CN disclosed
CN-1816547-A Oxazolidinone antibiotics and derivatives thereof MERCK & CO INC (US) 2006-08-09 CN disclosed
US-5087314-A Bonding materials with amine curable epoxy resin containing electroconductive particles of various shapes HARRIS CORPORATION (US) 1992-02-11 US disclosed