Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339826 | 0.78 | BBOX1 (0.41) | LMNAALDH1A1CYP2A6 | |
| Biphenyl SCHEMBL28807835 | 0.76 | ADRA2A (0.54) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| Benzene SCHEMBL27586265 | 0.74 | BBOX1 (0.39) | LMNAALDH1A1 | |
| SCHEMBL26417080 | 0.74 | BBOX1 (0.39) | LMNAALDH1A1 | |
| Bromide SCHEMBL9081012 | 0.74 | BBOX1 (0.39) | LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL30702244 | 0.74 | BBOX1 (0.39) | LMNAALDH1A1 | |
| Benzene SCHEMBL28143174 | 0.74 | LMNA (0.48) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| Toluene SCHEMBL27977943 | 0.74 | LMNA (0.61) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| Phenol SCHEMBL5875310 | 0.74 | CA12 (0.61) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL26500869 | 0.73 | TYR (0.38) | HIF1AKDM4EALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507035-A1 | Meadowsweet extracts, preparation and use thereof | SYNTHELABO (FR) | 1992-10-07 | — | — | EP | disclosed |