SCHEMBL9685555

SCHEMBL9685555

CC(=O)OCC(=O)Nc1cccc(C)c1CO

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.71
ALDH1A1 P00352 5/20 0.55
HSD17B10 Q99714 1/20 0.55
HPGD P15428 2/20 0.48
USP2 O75604 1/20 0.48
PKM P14618 1/20 0.47
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
KMT2A Q03164 1/20 0.45
GAA P10253 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
NPC1 O15118 2/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NLRP3 Q96P20 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9686504 0.87 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2
SCHEMBL28756536 0.83 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1HSD17B10HPGDLMNA
SCHEMBL9686546 0.81 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2
SCHEMBL9687683 0.80 HPGD (0.46) SMN1; SMN2ALDH1A1HSD17B10HPGDLMNA
SCHEMBL9687520 0.80 ALDH1A1 (0.61) SMN1; SMN2ALDH1A1HSD17B10HPGDMEN1
SCHEMBL9694548 0.79 HPGD (0.47) ALDH1A1HSD17B10HPGDPKMMEN1
Sulfuric Acid SCHEMBL28756597 0.78 SMN1; SMN2 (0.88) SMN1; SMN2ALDH1A1HSD17B10HPGDMEN1
SCHEMBL8175962 0.78 RAB9A (0.46) ALDH1A1HPGDMEN1LMNAKMT2A
SCHEMBL9686499 0.78 ALDH1A1 (0.57) SMN1; SMN2ALDH1A1HSD17B10HPGDMEN1
Nitric Acid SCHEMBL28756561 0.76 SMN1; SMN2 (0.83) SMN1; SMN2ALDH1A1HSD17B10HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed