SCHEMBL9686504

SCHEMBL9686504

CC(=O)OCC(=O)Nc1cccc(C)c1CCl

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.69
ALDH1A1 P00352 4/20 0.53
HSD17B10 Q99714 1/20 0.53
HPGD P15428 2/20 0.50
USP2 O75604 1/20 0.50
PKM P14618 1/20 0.46
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685555 0.87 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2
SCHEMBL28756536 0.82 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9686578 0.81 HPGD (0.45) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9687629 0.81 ALDH1A1 (0.59) SMN1; SMN2ALDH1A1HPGDPKMMAPT
SCHEMBL9686546 0.80 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2
SCHEMBL5901959 0.79 ALDH1A1 (0.47) ALDH1A1HPGDPKMMAPTGAA
SCHEMBL8192482 0.79 RAB9A (0.44) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL9687443 0.78 ALDH1A1 (0.60) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
Sulfuric Acid SCHEMBL28756597 0.77 SMN1; SMN2 (0.88) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9685711 0.76 POLB (0.50) ALDH1A1HSD17B10HPGDMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed