SCHEMBL9686546

SCHEMBL9686546

[CH2]c1c(C)cccc1NC(=O)COC(C)=O

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.73
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 1/20 0.56
HPGD P15428 2/20 0.49
USP2 O75604 1/20 0.49
PKM P14618 1/20 0.48
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 1/20 0.46
GAA P10253 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
POLB P06746 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28756536 0.84 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9685555 0.81 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2
SCHEMBL9686504 0.80 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2
SCHEMBL9687479 0.80 HPGD (0.47) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9685656 0.80 HPGD (0.48) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
Sulfuric Acid SCHEMBL28756597 0.79 SMN1; SMN2 (0.88) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9686240 0.78 CA1 (0.47) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9686605 0.77 ALDH1A1 (0.66) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
Nitric Acid SCHEMBL28756561 0.77 SMN1; SMN2 (0.83) SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT
SCHEMBL9686302 0.77 MAPK1 (0.57) ALDH1A1MEN1LMNAKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP claimed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US claimed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP claimed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed