SCHEMBL9686240

SCHEMBL9686240

[CH2]c1c(C)cccc1NC(=O)CN

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 5/20 0.46
ALOX12 P18054 1/20 0.46
MAPK1 P28482 3/20 0.45
ADRA2C P18825 1/20 0.45
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9687479 0.85 HPGD (0.47) ALDH1A1MAPTHSD17B10HPGDALOX12
SCHEMBL9685656 0.85 HPGD (0.48) ALDH1A1MAPTHSD17B10HPGDALOX12
SCHEMBL28947962 0.83 MAPT (0.65) ALDH1A1MAPTHSD17B10HPGDMAPK1
SCHEMBL29575287 0.82 HPGD (0.66) CA1CA2ALDH1A1MAPTHSD17B10
SCHEMBL7284784 0.82 HPGD (0.66) CA1CA2ALDH1A1MAPTHSD17B10
SCHEMBL9686302 0.82 MAPK1 (0.57) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL9685670 0.81 POLB (0.54) ALDH1A1MAPTHSD17B10HPGDALOX12
SCHEMBL9686605 0.79 ALDH1A1 (0.66) ALDH1A1MAPTHSD17B10HPGDMAPK1
SCHEMBL6717728 0.79 LMNA (0.52) CA1CA2ALDH1A1MAPTHSD17B10
SCHEMBL9686546 0.78 SMN1; SMN2 (0.73) ALDH1A1MAPTHSD17B10HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP claimed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US claimed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP claimed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed