Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553869 | 0.84 | KEAP1 (0.62) | KEAP1NFE2L2GLO1NR3C1ALDH1A1 | |
| SCHEMBL9687772 | 0.83 | KEAP1 (0.61) | KEAP1NFE2L2GLO1NR3C1ALDH1A1 | |
| SCHEMBL7888370 | 0.83 | KEAP1 (0.61) | KEAP1NFE2L2GLO1NR3C1ALDH1A1 | |
| SCHEMBL28728662 | 0.80 | LMNA (0.56) | KEAP1NFE2L2ALDH1A1L3MBTL1HTT | |
| Acetic Acid SCHEMBL1627928 | 0.76 | KEAP1 (0.53) | KEAP1NFE2L2GLO1NR3C1ALDH1A1 | |
| SCHEMBL15108064 | 0.76 | KEAP1 (1.00) | KEAP1NFE2L2GLO1NR3C1ALDH1A1 | |
| SCHEMBL1476351 | 0.75 | KEAP1 (0.70) | KEAP1NFE2L2GLO1ALDH1A1PTGS1 | |
| SCHEMBL9685775 | 0.74 | CYP3A4 (0.35) | KEAP1NFE2L2ALDH1A1HTTJAK2 | |
| SCHEMBL8192482 | 0.74 | RAB9A (0.44) | ALDH1A1PTGS2 | |
| SCHEMBL11516751 | 0.74 | KEAP1 (0.68) | KEAP1NFE2L2GLO1ALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |