Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685774 | 0.82 | CYP3A4 (0.38) | CYP3A4CYP2D6ALDH1A1TSHRCYP1A2 | |
| SCHEMBL7123694 | 0.76 | LMNA (0.40) | CYP3A4CYP2D6ALDH1A1TSHRHTT | |
| SCHEMBL8192482 | 0.75 | RAB9A (0.44) | ALDH1A1NPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL4776892 | 0.75 | KEAP1 (0.52) | CYP3A4CYP2D6ALDH1A1TSHRCYP1A2 | |
| SCHEMBL9800976 | 0.74 | NPC1 (0.50) | ALDH1A1TSHRHTTMAPTPABPC1 | |
| SCHEMBL225741 | 0.74 | NPC1 (0.50) | ALDH1A1TSHRHTTMAPTPABPC1 | |
| SCHEMBL9687629 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP2C19HTTMAPT | |
| SCHEMBL9685752 | 0.74 | KEAP1 (0.61) | ALDH1A1HTTJAK2KEAP1NFE2L2 | |
| SCHEMBL459954 | 0.73 | CYP2A6 (0.43) | ALDH1A1TSHRCYP1A2HTTMAPT | |
| SCHEMBL9840547 | 0.73 | TSHR (0.39) | CYP3A4CYP2D6ALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |