SCHEMBL9686008

SCHEMBL9686008

CO[SiH](CCl)Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
CALM1 P0DP23 1/20 0.33
KCNH2 Q12809 1/20 0.33
ALDH1A1 P00352 3/20 0.32
IDO1 P14902 1/20 0.32
ABCB1 P08183 1/20 0.32
TTR P02766 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482739 0.87 TP53 (0.42) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL3808418 0.81 TP53 (0.42) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL27725786 0.78 TP53 (0.39) LTA4HTP53TSHRSIGMAR1CALM1
SCHEMBL4195238 0.74 LTA4H (0.39) LTA4HTP53TSHRSIGMAR1CALM1
SCHEMBL5180297 0.73 SIGMAR1 (0.40) LTA4HTP53SIGMAR1KCNH2
SCHEMBL49102 0.73 TP53 (0.42) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL28446741 0.72 TSHR (0.43) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL9505652 0.71 TP53 (0.40) LTA4HTP53TSHRCALM1KCNH2
SCHEMBL7058982 0.71 TP53 (0.40) LTA4HTP53TSHRCALM1ALDH1A1
(Chloromethyl)Benzene SCHEMBL8577748 0.70 TTR (0.41) LTA4HTP53TSHRSIGMAR1CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096991-A Monomer from dihydroxy aromatic compound and haloalkylsilanol, elasticity, strength SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-17 US disclosed