SCHEMBL9686151

SCHEMBL9686151

O=C1NC(=O)c2c1cccc2C(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 5/20 0.51
AKR1C3 P42330 1/20 0.47
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 4/20 0.46
GAA P10253 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 1/20 0.46
GSK3B P49841 2/20 0.45
POLB P06746 2/20 0.45
MAPT P10636 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
HTT P42858 2/20 0.44
APAF1 O14727 1/20 0.44
MAPK1 P28482 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11612938 0.93 KDM4E (0.49) CASP3ALDH1A1KDM4EGAAHPGD
Diphenylether SCHEMBL3762390 0.83 MAOA (0.50) CASP3ALDH1A1KDM4EGAAHPGD
SCHEMBL439731 0.82 LIG1 (0.56) CASP3ALDH1A1KDM4EGAAHPGD
SCHEMBL30641073 0.81 KMT2A (0.51) CASP3ALDH1A1KDM4EGAAHPGD
Benzophenone SCHEMBL20702109 0.80 GSK3B (0.65) CASP3ALDH1A1HPGDHSD17B10GSK3B
SCHEMBL6562742 0.78 KDM4E (0.49) CASP3ALDH1A1KDM4EGAAHPGD
SCHEMBL10349769 0.78 ALDH1A1 (0.54) CASP3ALDH1A1KDM4EGAAHPGD
SCHEMBL10339858 0.77 KEAP1 (0.56) CASP3ALDH1A1KDM4EGAAHPGD
SCHEMBL5128860 0.77 KDM4E (0.58) CASP3ALDH1A1KDM4EGAAHPGD
SCHEMBL11358929 0.77 KDM4E (0.54) CASP3ALDH1A1KDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US claimed
US-5118783-A Polymerizing polyhydric alchols with unsaturated dicarboxylic acid or anhydride, chain termination by monofunctional acid or alcohol REICHHOLD CHEMICALS, INC. (US) 1992-06-02 US disclosed
EP-0475661-A2 Chain-stopped unsaturated polyester resin REICHHOLD CHEMICALS, INC. (US) 1992-03-18 EP disclosed
US-4200731-A REACTION WITH N-BENZOYLLACTAM OR N-BENZOYLPHTHALIMIDE TO FORM BENZOYL ENDCAPS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-04-29 US disclosed
US-4200731-A REACTION WITH N-BENZOYLLACTAM OR N-BENZOYLPHTHALIMIDE TO FORM BENZOYL ENDCAPS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-04-29 US disclosed