Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109607 | 0.97 | TP53 (0.48) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| Fluoride Ion SCHEMBL10938266 | 0.94 | TP53 (0.46) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| Water SCHEMBL3190778 | 0.94 | TP53 (0.46) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| Bromide SCHEMBL7106052 | 0.94 | TP53 (0.46) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| Iodide SCHEMBL10884304 | 0.94 | TP53 (0.46) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| SCHEMBL29441851 | 0.87 | TP53 (0.40) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| SCHEMBL8757718 | 0.87 | TP53 (0.40) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| Hydrochloric Acid SCHEMBL8990690 | 0.85 | KDM4E (0.32) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL1135134 | 0.84 | TP53 (0.37) | ALDH1A1KDM4ETDP1TP53CALM1 | |
| Phosphoric Acid SCHEMBL11528106 | 0.84 | TSHR (0.38) | ALDH1A1KDM4ETDP1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100172961-A1 | Encapsulated Peptide Amphiphile Nanostructures | NORTHWESTERN UNIVERSITY (US) | 2010-07-08 | — | — | US | claimed |
| WO-2008063808-A2 | ENCAPSULATED PEPTIDE AMPHIPHILE NANOSTRUCTURES | NORTHWESTERN UNIVERSITY (US) | 2008-05-29 | — | — | WO | claimed |
| US-20110015442-A1 | SULFONE COMPOUND AND METHOD FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110015441-A1 | SULFONE COMPOUND AND PROCESS FOR PRODUCING CAROTENOID USING THE SAME COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-20 | — | — | US | disclosed |
| EP-2261204-A1 | SULFONE COMPOUND AND METHOD FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-12-15 | — | — | EP | disclosed |
| EP-2253613-A1 | SULFONE COMPOUND AND CAROTENOID MANUFACTURING METHOD USING SAID COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-20100172961-A1 | Encapsulated Peptide Amphiphile Nanostructures | NORTHWESTERN UNIVERSITY (US) | 2010-07-08 | — | — | US | disclosed |
| WO-2008063808-A2 | ENCAPSULATED PEPTIDE AMPHIPHILE NANOSTRUCTURES | NORTHWESTERN UNIVERSITY (US) | 2008-05-29 | — | — | WO | disclosed |
| EP-1231197-A1 | Process for producing allyl halide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-20020107422-A1 | Process for producing allyl halide compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2002-08-08 | — | — | US | disclosed |
| EP-0621313-B1 | Epoxy resin composition | MITSUI CHEMICALS INC (JP) | 1998-07-15 | — | — | EP | disclosed |
| EP-0293237-B1 | Epoxy compounds and epoxy resin compositions containing the same | MITSUI PETROCHEMICAL IND (JP) | 1994-07-27 | — | — | EP | disclosed |
| EP-0251431-B1 | EPOXY RESIN | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-4954603-A | Epoxy resin | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4900801-A | AROMATIC RINGS HAVING A TERTIARY ALKYL ORTHO TO THE GLYCIDYL RADICAL; CURED POLYMERS HAVING LOW DIELECTRIC CONSTANT; HEATTP RESISTANCE; FLEXIBILITY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-13 | — | — | US | disclosed |
| US-4835240-A | Epoxy resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0294148-A2 | Epoxy resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-07 | — | — | EP | disclosed |
| EP-0293237-A2 | Epoxy compounds and epoxy resin compositions containing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| EP-0251431-A2 | Epoxy resin | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4233202-A | ADSORPTION OF CATALYST FROM MIXTURE OF EPIHALOHYDRIN AND GLYCIDYLATED PRODUCT | CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015442-A1 | SULFONE COMPOUND AND METHOD FOR PRODUCING THE SAME | MSRB3, HCN4, SULT1E1 | SLC6A2 2947/4885SLC6A3 1450/4885ALDH1A1 2501/4885 |
| US-20110015441-A1 | SULFONE COMPOUND AND PROCESS FOR PRODUCING CAROTENOID USING THE SAME COMPOUND | SCLY, ENY2, ZYX | SLC6A2 3932/4885SLC6A3 2232/4885ALDH1A1 1424/4885 |
| US-20020107422-A1 | Process for producing allyl halide compound | ENY2, ZYX, RPS4Y1 | SLC6A2 4630/4885SLC6A3 4594/4885ALDH1A1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.