SCHEMBL9686484

SCHEMBL9686484

[CH2]c1c(C)cccc1N(S)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.32
DRD2 P14416 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2B P41595 1/20 0.32
MYC P01106 1/20 0.32
GAA P10253 1/20 0.32
LMNA P02545 3/20 0.31
PKM P14618 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
ALDH1A1 P00352 3/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PARP1 P09874 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919799 0.82 SIGMAR1 (0.42) SIGMAR1MYCGAALMNAALDH1A1
SCHEMBL10561473 0.81 SIGMAR1 (0.39) SIGMAR1DRD2HTR2AHTR2BMYC
SCHEMBL11174076 0.76 MYC (0.36) DRD2HTR2AHTR2BMYCPKM
SCHEMBL5898505 0.74 GAA (0.40) GAALMNAALDH1A1KDM4EPARP1
SCHEMBL10691288 0.73 EPHX1 (0.45) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL10560497 0.71 TSPO (0.44) SIGMAR1GAALMNAALDH1A1MEN1
SCHEMBL10431122 0.69 ALDH1A1 (0.52) GAALMNAALDH1A1KDM4EHPGD
SCHEMBL27490383 0.69 MAPT (0.44) SIGMAR1GAALMNAALDH1A1KDM4E
SCHEMBL1116304 0.68 CYP3A4 (0.36) GAAALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1116324 0.68 KDM4E (0.43) HTR2BGAALMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP claimed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US claimed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP claimed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
CN-87108027-A Imidazopyridine and preparation method thereof 1988-06-08 CN disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed