Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688018 | 0.91 | MEN1 (0.49) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9164648 | 0.85 | KMT2A (0.47) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9686909 | 0.75 | KMT2A (0.46) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9688130 | 0.72 | LMNA (0.43) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL9026198 | 0.70 | LMNA (0.39) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9687941 | 0.65 | EZH2 (0.40) | KMT2AKDM4ESMN1; SMN2MEN1HTT | |
| SCHEMBL1482126 | 0.63 | MAPT (0.73) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL17669252 | 0.63 | MAPT (0.71) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL15801114 | 0.63 | MAPT (0.71) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9687454 | 0.62 | MEN1 (0.39) | ALDH1A1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |