Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687409 | 0.81 | LMNA (0.43) | MAPTTSHRMAPK1EPHX2 | |
| SCHEMBL9687701 | 0.72 | TRPV1 (0.51) | — | |
| SCHEMBL19562231 | 0.65 | F10 (0.55) | F10MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL9164617 | 0.64 | NPC1 (0.51) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL9026831 | 0.64 | IDO1 (0.45) | — | |
| SCHEMBL30064685 | 0.64 | SIGMAR1 (0.56) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL17513187 | 0.63 | VEGFA (0.59) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL9280239 | 0.63 | RXFP1 (0.45) | MAPTALDH1A1TSHR | |
| SCHEMBL17005985 | 0.62 | VEGFA (0.62) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL9278822 | 0.61 | RAB9A (0.46) | MAPTALDH1A1TSHRMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |