Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991744 | 0.87 | PTGS2 (0.53) | GAAKMT2AKDM4EHTTMAPK10 | |
| SCHEMBL6195246 | 0.87 | GAA (0.49) | GAAKMT2AKDM4EHTTMEN1 | |
| SCHEMBL6775469 | 0.85 | GAA (0.45) | GAAKMT2AKDM4EHTTMEN1 | |
| SCHEMBL4686135 | 0.77 | TSHR (0.59) | KMT2AKDM4EHTTMAPK10MEN1 | |
| SCHEMBL28257930 | 0.75 | TPMT (0.60) | GAAKMT2AKDM4EHTTALDH1A1 | |
| SCHEMBL6462475 | 0.74 | ALOX5 (0.51) | GAAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7046945 | 0.73 | PTGS2 (0.57) | GAAKMT2AKDM4EMAPK10MEN1 | |
| SCHEMBL16933701 | 0.73 | ALDH1A1 (0.50) | GAAKMT2AKDM4EHTTMEN1 | |
| SCHEMBL14939021 | 0.73 | TUBB1 (0.39) | HTTLMNA | |
| SCHEMBL4965033 | 0.72 | PTGS2 (0.55) | GAAKMT2AKDM4EMAPK10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201575-B1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| US-4686230-A | Picoline derivative useful as gastric acid secretion inhibitors | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-08-11 | — | — | US | disclosed |