Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617147 | 1.00 | CHRM1 (0.38) | CHRM1CYP19A1KMT2AACEFAAH | |
| SCHEMBL6399031 | 0.83 | CYP19A1 (0.31) | CYP19A1SIGMAR1 | |
| SCHEMBL7591812 | 0.82 | CHRM1 (0.40) | CHRM1CYP19A1KMT2AFAAHMGLL | |
| SCHEMBL9686556 | 0.82 | UCHL1 (0.44) | KMT2AACEECE1CYP3A4POLB | |
| SCHEMBL8833609 | 0.76 | ECE1 (0.38) | CHRM1CYP19A1KMT2AFAAHMGLL | |
| SCHEMBL9215980 | 0.75 | ECE1 (0.37) | CHRM1CYP19A1KMT2AFAAHMGLL | |
| SCHEMBL8833492 | 0.75 | ECE1 (0.37) | CHRM1CYP19A1KMT2AFAAHMGLL | |
| SCHEMBL9220923 | 0.75 | ECE1 (0.36) | CHRM1CYP19A1KMT2AECE1MEN1 | |
| SCHEMBL9027722 | 0.75 | ECE1 (0.38) | CHRM1CYP19A1KMT2AACEFAAH | |
| SCHEMBL8833239 | 0.75 | ECE1 (0.36) | CHRM1CYP19A1KMT2AECE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |