Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108092 | 0.74 | AKT1 (0.39) | AKT1CTSLCTSBCTSSSMN1; SMN2 | |
| SCHEMBL9686985 | 0.73 | LCK (0.43) | TSHRLCKLMNANPC1RAB9A | |
| SCHEMBL6433906 | 0.71 | NQO2 (0.54) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12060874 | 0.70 | AKT1 (0.48) | AKT1CTSLCTSBCTSSLCK | |
| SCHEMBL6233792 | 0.69 | AKT1 (0.44) | AKT1CTSLCTSBCTSSLCK | |
| SCHEMBL20558403 | 0.69 | KDM4A (0.43) | CTSSMAPK1 | |
| SCHEMBL10561041 | 0.68 | TRPM8 (0.40) | SMN1; SMN2ALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL9687613 | 0.68 | L3MBTL1 (0.42) | SMN1; SMN2ALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL10560390 | 0.67 | TSHR (0.35) | SMN1; SMN2ALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL2556108 | 0.67 | MTNR1A (0.42) | SMN1; SMN2ALDH1A1LCKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |