Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689963 | 0.87 | HDAC3 (0.43) | ALDH1A1KDM4EPRNPHPGDRAB9A | |
| SCHEMBL9688900 | 0.83 | KDM4E (0.41) | ALDH1A1KDM4EPRNPHPGDRAB9A | |
| SCHEMBL9689969 | 0.78 | HDAC3 (0.39) | ALDH1A1KDM4EPRNPHPGDRAB9A | |
| SCHEMBL9689433 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EPRNPHPGDRAB9A | |
| SCHEMBL9689487 | 0.76 | HDAC6 (0.43) | ALDH1A1KDM4EPRNPHPGDRAB9A | |
| SCHEMBL9688557 | 0.75 | KDM4E (0.40) | ALDH1A1KDM4EPRNPHPGDRAB9A | |
| SCHEMBL9688573 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EPRNPHPGDRAB9A | |
| SCHEMBL9690025 | 0.74 | PPARA (0.42) | ALDH1A1KDM4ERAB9ATP53NPC1 | |
| SCHEMBL9689951 | 0.74 | TDP1 (0.41) | KDM4ERAB9AMAPTNPC1KMT2A | |
| SCHEMBL9690023 | 0.73 | KDM4E (0.38) | ALDH1A1KDM4EPRNPHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |