Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689487 | 0.88 | HDAC6 (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9688900 | 0.87 | KDM4E (0.41) | HDAC1HDAC6ALDH1A1RAB9AKDM4E | |
| SCHEMBL9690025 | 0.80 | PPARA (0.42) | HDAC6ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9688550 | 0.78 | ALDH1A1 (0.42) | ALDH1A1RAB9ANPC1KDM4EHPGD | |
| SCHEMBL9689971 | 0.75 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL9689963 | 0.74 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9688521 | 0.71 | SIGMAR1 (0.38) | ALDH1A1RAB9AKDM4EHPGDPRNP | |
| SCHEMBL9469004 | 0.70 | TDP1 (0.42) | ALDH1A1KDM4EKMT2APOLBLMNA | |
| SCHEMBL8947138 | 0.69 | KMT2A (0.49) | HDAC6ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL9689433 | 0.68 | ALDH1A1 (0.49) | ALDH1A1RAB9AKDM4EHPGDPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |