Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689969 | 0.87 | HDAC3 (0.39) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9689487 | 0.85 | HDAC6 (0.43) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9688550 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9689951 | 0.83 | TDP1 (0.41) | KDM4ERAB9ACYP1A2PTGS2CA2 | |
| SCHEMBL9690025 | 0.83 | PPARA (0.42) | KDM4EALDH1A1RAB9ACYP1A2PTGS2 | |
| SCHEMBL9689963 | 0.80 | HDAC3 (0.43) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9690648 | 0.79 | NPSR1 (0.38) | ALOX5PTGESLMNA | |
| SCHEMBL9469004 | 0.76 | TDP1 (0.42) | KDM4EALDH1A1DGAT1CYP1A2LMNA | |
| SCHEMBL8947138 | 0.76 | KMT2A (0.49) | KDM4EALDH1A1CYP1A2PTGS2LMNA | |
| SCHEMBL9689433 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1PRNPHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |