Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120045 | 0.75 | HTT (0.38) | HTTALDH1A1ICMT | |
| SCHEMBL13980116 | 0.72 | MEN1 (0.33) | MEN1ALDH1A1MAPTKMT2ASCN5A | |
| SCHEMBL2531130 | 0.71 | ALDH1A1 (0.40) | HTTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8680142 | 0.70 | HTT (0.33) | ATMHTTMEN1ALDH1A1MAPT | |
| SCHEMBL12433432 | 0.70 | MEN1 (0.36) | ATMLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL31484258 | 0.69 | GRIN2D (0.33) | HTTALDH1A1ICMT | |
| SCHEMBL29718486 | 0.68 | L3MBTL1 (0.43) | L3MBTL1LMNAHTTMEN1ALDH1A1 | |
| SCHEMBL8679249 | 0.68 | HTT (0.32) | ATMHTTRAB9A | |
| SCHEMBL25527063 | 0.68 | MEN1 (0.33) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12569788 | 0.67 | IRAK4 (0.44) | L3MBTL1ATMLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201575-B1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| US-4686230-A | Picoline derivative useful as gastric acid secretion inhibitors | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-08-11 | — | — | US | disclosed |