Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777752 | 0.86 | KCNJ5 (0.44) | L3MBTL1KMT2ACXCL8SMN1; SMN2HTT | |
| SCHEMBL29718735 | 0.84 | CXCL8 (0.58) | L3MBTL1KMT2ACXCL8ALKBH1CYP2D6 | |
| SCHEMBL3135922 | 0.84 | CXCL8 (0.58) | L3MBTL1KMT2ACXCL8ALKBH1CYP2D6 | |
| SCHEMBL22994473 | 0.80 | HPGD (0.45) | L3MBTL1KMT2ASMN1; SMN2HTTTNF | |
| SCHEMBL24603013 | 0.80 | L3MBTL1 (0.47) | L3MBTL1KMT2ACXCL8MAP3K7TAB1 | |
| SCHEMBL909198 | 0.78 | TBXAS1 (0.48) | L3MBTL1KMT2ASMN1; SMN2TNFMEN1 | |
| SCHEMBL28115191 | 0.78 | CYP1A2 (0.41) | L3MBTL1KMT2ACXCL8SMN1; SMN2HTT | |
| SCHEMBL1010680 | 0.77 | LMNA (0.64) | L3MBTL1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL16830102 | 0.76 | MTNR1A (0.52) | KMT2AMAPK1 | |
| SCHEMBL10565876 | 0.76 | GRIN2B (0.48) | L3MBTL1CXCL8SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023190826-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS | 学校法人 高崎健康福祉大学 | 2023-10-05 | — | — | WO | disclosed |
| CN-109415321-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-06-17 | — | — | CN | disclosed |