Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690712 | 0.88 | MAPT (0.43) | MAPTNPC1RAB9ALMNANPSR1 | |
| SCHEMBL1664963 | 0.86 | SMN1; SMN2 (0.50) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9690728 | 0.80 | RXFP1 (0.46) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9844400 | 0.75 | KDM4E (0.41) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL9689145 | 0.75 | TP53 (0.35) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL9691174 | 0.73 | CYP17A1 (0.49) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL9689162 | 0.72 | MAPT (0.47) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL9690785 | 0.69 | DGAT1 (0.46) | MAPTLMNAALDH1A1TSHRGABRA1 | |
| SCHEMBL9691055 | 0.69 | HSD11B1 (0.45) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL9690834 | 0.69 | PDE2A (0.46) | NPC1RAB9ANPSR1SMN1; SMN2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060843-A | TRIAZOLOPYRIDAZINE DERIVATES | RHONE POULENC AGROCHIMIE (FR) | 1992-05-06 | — | — | CN | disclosed |
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |