Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 8/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972329 | 0.78 | GNAI3 (0.41) | GNAO1GNAI3GNAI1 | |
| SCHEMBL14893358 | 0.78 | KDM1A (0.33) | — | |
| SCHEMBL15925128 | 0.76 | DPP4 (0.41) | KCNH2 | |
| SCHEMBL8972223 | 0.74 | MAPT (0.44) | GNAO1GNAI3GNAI1KCNH2 | |
| SCHEMBL22930466 | 0.72 | GNAO1 (0.42) | GNAO1GNAI3GNAI1KCNH2 | |
| SCHEMBL1842886 | 0.71 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL8972506 | 0.71 | GNAI3 (0.37) | GNAO1GNAI3GNAI1 | |
| SCHEMBL18533791 | 0.71 | TLR9 (0.36) | GNAO1GNAI3GNAI1 | |
| Hydrochloric Acid SCHEMBL8972944 | 0.70 | GNAI3 (0.39) | GNAO1GNAI3GNAI1 | |
| SCHEMBL24490092 | 0.70 | GNAO1 (0.43) | GNAO1GNAI3GNAI1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468457-A1 | Novel substituted piperidines and their use as inhibitors of cholesterol synthesis | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |