Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688657 | 0.76 | DRD2 (0.44) | TAAR1NEK1KDM4E | |
| SCHEMBL9688896 | 0.75 | HTR2A (0.47) | HTR2ATAAR1ADRA1AKDM4EATM | |
| SCHEMBL9688747 | 0.74 | ALDH1A1 (0.51) | KDM4E | |
| SCHEMBL1190039 | 0.74 | ADRB2 (0.44) | HTR2ATAAR1ADRA1ANEK1 | |
| Hydrochloric Acid SCHEMBL1190213 | 0.72 | ADRB2 (0.43) | HTR2ATAAR1ADRA1ANEK1 | |
| SCHEMBL7281232 | 0.72 | HTR2A (0.50) | HTR2ATAAR1ADRA1ANEK1KDM4E | |
| SCHEMBL9689779 | 0.71 | HTR2A (0.43) | HTR2ATAAR1ADRA1AKDM4EATM | |
| SCHEMBL24498666 | 0.69 | HTR2A (0.57) | HTR2ATAAR1ADRA1A | |
| SCHEMBL11816292 | 0.68 | TAAR1 (0.58) | HTR2ATAAR1ADRA1A | |
| SCHEMBL8303296 | 0.67 | TAAR1 (0.52) | HTR2ATAAR1ADRA1AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189473-B1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0189473-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS. | SCHERING AG (DE) | 1986-08-06 | — | — | EP | disclosed |
| WO-1986001204-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-02-27 | — | — | WO | disclosed |