Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690023 | 0.84 | KDM4E (0.38) | APPALDH1A1HPGDKDM4EPRNP | |
| SCHEMBL9469693 | 0.79 | KDM4E (0.46) | ALDH1A1HPGDKDM4EPRNPRAB9A | |
| SCHEMBL9688895 | 0.78 | KDM4E (0.43) | ALDH1A1HPGDKDM4EPRNPRAB9A | |
| SCHEMBL9689433 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EPRNPRAB9A | |
| SCHEMBL9688573 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EPRNPRAB9A | |
| SCHEMBL8947138 | 0.76 | KMT2A (0.49) | ALDH1A1KDM4EKMT2ALMNAHTT | |
| SCHEMBL9689439 | 0.75 | KDM4E (0.45) | ALDH1A1HPGDKDM4EPRNPRAB9A | |
| SCHEMBL9688557 | 0.75 | KDM4E (0.40) | ALDH1A1HPGDKDM4EPRNPRAB9A | |
| SCHEMBL9688900 | 0.73 | KDM4E (0.41) | APPALDH1A1HPGDKDM4EPRNP | |
| SCHEMBL9690027 | 0.73 | HDAC6 (0.38) | ALDH1A1KDM4ERAB9AKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |