Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689971 | 0.86 | ALDH1A1 (0.35) | KDM4EKMT2AALDH1A1HPGDPRNP | |
| SCHEMBL9689482 | 0.84 | ALDH1A1 (0.34) | KDM4EKMT2AALDH1A1HPGDPRNP | |
| SCHEMBL9689940 | 0.82 | TDP1 (0.40) | KDM4EALDH1A1HPGDHSD17B10GPR139 | |
| SCHEMBL9690031 | 0.82 | TDP1 (0.40) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL9689975 | 0.81 | GPR139 (0.37) | KDM4EKMT2AALDH1A1HPGDPRNP | |
| SCHEMBL9689439 | 0.80 | KDM4E (0.45) | KDM4EKMT2AALDH1A1HPGDPRNP | |
| SCHEMBL9469693 | 0.79 | KDM4E (0.46) | KDM4EKMT2AALDH1A1HPGDPRNP | |
| SCHEMBL9689433 | 0.78 | ALDH1A1 (0.49) | KDM4EKMT2AALDH1A1HPGDPRNP | |
| SCHEMBL9688569 | 0.78 | KDM4E (0.43) | KDM4EKMT2AALDH1A1HPGDPRNP | |
| SCHEMBL9689989 | 0.78 | APP (0.45) | KDM4EKMT2AALDH1A1HPGDPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |