Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691130 | 0.75 | HSD11B1 (0.43) | GABRA1GABRG2GABRB3GABRA2NPSR1 | |
| SCHEMBL9689111 | 0.73 | KDM4E (0.46) | HPGDHSD17B10LMNAKDM4EMAPT | |
| SCHEMBL9689092 | 0.73 | GABRA1 (0.37) | ALDH1A1HPGDHSD17B10LMNACYP1A2 | |
| SCHEMBL9690137 | 0.72 | CYP2A6 (0.46) | ALDH1A1HPGDHSD17B10LMNACYP1A2 | |
| SCHEMBL2747352 | 0.71 | HSD11B1 (0.55) | ALDH1A1HPGDHSD17B10MAPTGAA | |
| SCHEMBL18323596 | 0.71 | KDM4E (0.50) | ALDH1A1HPGDHSD17B10LMNACYP1A2 | |
| SCHEMBL9691180 | 0.71 | HPGD (0.56) | ALDH1A1HPGDHSD17B10LMNACYP1A2 | |
| SCHEMBL9691041 | 0.71 | RAB9A (0.36) | ALDH1A1HPGDHSD17B10LMNACYP1A2 | |
| SCHEMBL9691208 | 0.69 | RXFP1 (0.48) | ALDH1A1HPGDHSD17B10KDM4EALOX15 | |
| SCHEMBL9690839 | 0.69 | HPGD (0.41) | ALDH1A1HPGDHSD17B10LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |