Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | TP53 | P04637 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9630404 | 0.96 | SLC6A9 (0.43) | SLC6A9ENPP2MAPTTP53POLB | |
| SCHEMBL9691136 | 0.89 | SLC6A9 (0.44) | SLC6A9ENPP2MAPTTP53POLB | |
| Fumaric Acid SCHEMBL9630608 | 0.88 | SLC6A9 (0.43) | SLC6A9ENPP2MAPTTP53POLB | |
| SCHEMBL9690993 | 0.87 | SLC6A9 (0.46) | SLC6A9ENPP2MAPTTP53POLB | |
| SCHEMBL9629312 | 0.86 | SLC6A9 (0.47) | SLC6A9ENPP2MAPTTP53POLB | |
| SCHEMBL9688954 | 0.85 | MEN1 (0.42) | ENPP2MAPTTP53 | |
| SCHEMBL9629392 | 0.85 | TP53 (0.40) | ENPP2MAPTTP53LMNA | |
| SCHEMBL9564788 | 0.84 | ALDH1A1 (0.38) | SLC6A9MAPTTP53LMNA | |
| SCHEMBL9629649 | 0.82 | SLC6A9 (0.44) | SLC6A9ENPP2MAPTTP53POLB | |
| SCHEMBL9629472 | 0.82 | SLC6A9 (0.38) | SLC6A9ENPP2MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297661-B1 | [(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-09-16 | — | — | EP | disclosed |
| EP-0297661-A1 | [(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-01-04 | — | — | EP | disclosed |