Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891427 | 0.80 | SCN2A (0.50) | ALDH1A1TDP1NR1H2S100A4PTPRC | |
| SCHEMBL9503453 | 0.78 | S100A4 (0.58) | ALDH1A1TDP1LMNAS100A4PTPRC | |
| SCHEMBL15577172 | 0.72 | ERCC1 (0.55) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL29763759 | 0.69 | HNF4A (0.44) | ALDH1A1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL7993799 | 0.69 | NR1H2 (0.42) | ALDH1A1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29575337 | 0.68 | TDP1 (0.71) | ALDH1A1TDP1LMNAS100A4PTPRC | |
| SCHEMBL9444834 | 0.68 | TDP1 (0.71) | ALDH1A1TDP1LMNAS100A4PTPRC | |
| SCHEMBL28806770 | 0.68 | HNF4A (0.43) | ALDH1A1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL22636895 | 0.68 | ALDH1A1 (0.42) | ALDH1A1TDP1LMNASCN2AMEN1 | |
| SCHEMBL11333782 | 0.67 | S100A4 (0.66) | ALDH1A1TDP1LMNAS100A4PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322401-B1 | TETRAHYDROPHTHALIMIDE DERIVATIVES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |