Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16116061 | 0.78 | LMNA (0.33) | LMNAMEN1KMT2AMAPTGAA | |
| SCHEMBL1354899 | 0.71 | ALDH1A1 (0.36) | CYP2C9LMNAMEN1KMT2AMAPT | |
| SCHEMBL9844880 | 0.70 | MAOA (0.38) | CYP2C9LMNAMEN1KMT2AMAPT | |
| SCHEMBL1028466 | 0.67 | HTR2A (0.39) | LMNAALDH1A1ATMHSD17B10KDM4E | |
| SCHEMBL501810 | 0.67 | GAA (0.65) | CYP2C9LMNAMEN1KMT2AMAPT | |
| Ammonia Solution, Strong SCHEMBL21245914 | 0.66 | HTR2A (0.38) | LMNAALDH1A1ATMHSD17B10KDM4E | |
| SCHEMBL9145856 | 0.66 | HTR2A (0.38) | LMNAALDH1A1ATMHSD17B10KDM4E | |
| Methane SCHEMBL28813011 | 0.66 | HTR2A (0.38) | LMNAALDH1A1ATMHSD17B10KDM4E | |
| SCHEMBL9145143 | 0.66 | HTR2A (0.38) | LMNAALDH1A1ATMHSD17B10KDM4E | |
| Lithium SCHEMBL9145147 | 0.66 | HTR2A (0.38) | LMNAALDH1A1ATMHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187524-B1 | A DIARYL BUTYRIC ACID DERIVATIVE AND THE PRODUCTION PROCESS THEREOF | SUNTORY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4766116-A | NERVOUS SYSTEM DISORDERS | SUNTORY LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0187524-A2 | A diaryl butyric acid derivative and the production process thereof | SUNTORY LIMITED (JP) | 1986-07-16 | — | — | EP | disclosed |