Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474241 | 0.85 | PDE10A (0.42) | HPGDALDH1A1KDM4ECYP1A2RAB9A | |
| SCHEMBL9702156 | 0.82 | NPC1 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4PDGFRB | |
| SCHEMBL6877250 | 0.74 | METAP2 (0.51) | HPGDALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL10865814 | 0.74 | KDM4E (0.51) | HPGDALDH1A1KDM4ENR4A2CYP1A2 | |
| SCHEMBL6877256 | 0.74 | ALDH1A1 (0.40) | HPGDALDH1A1KDM4ENR4A2CYP1A2 | |
| SCHEMBL11188068 | 0.72 | NPC1 (0.46) | HPGDALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL10703634 | 0.69 | EGFR (0.40) | HPGDALDH1A1KDM4ETP53KMT2A | |
| SCHEMBL9823497 | 0.69 | TUBB4A (0.45) | HPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL9823659 | 0.68 | PDE7A (0.46) | HPGDALDH1A1KDM4ECYP3A4SMN1; SMN2 | |
| SCHEMBL10617569 | 0.67 | CYP1A2 (0.34) | HPGDALDH1A1KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |