Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693697 | 0.85 | HPGD (0.39) | KMT2AHPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9702156 | 0.85 | NPC1 (0.43) | PDE10AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9377071 | 0.78 | PDE10A (0.36) | PDE10AMAPTMEN1KMT2AHTT | |
| SCHEMBL9377647 | 0.77 | LOXL2 (0.45) | PDE10AHTTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL9695439 | 0.75 | KDM4E (0.37) | MAPTMEN1KMT2AHTTHPGD | |
| Hydrochloric Acid SCHEMBL9756590 | 0.72 | HRH1 (0.42) | MAPTKMT2ASMN1; SMN2HRH1LIN28A | |
| SCHEMBL11253725 | 0.72 | MAOA (0.43) | MAPTKMT2AHTTSMN1; SMN2HRH1 | |
| SCHEMBL9693698 | 0.71 | ATP4A (0.36) | PDE10AMAPTMEN1KMT2AHTT | |
| Timoprazole SCHEMBL464728 | 0.71 | CYP1A2 (0.51) | MAPTMEN1KMT2AHTTHPGD | |
| Timoprazole SCHEMBL9247237 | 0.71 | CYP1A2 (0.51) | MAPTMEN1KMT2AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010047038-A1 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | MOORMAN ALAN E (US) | 2001-11-29 | — | — | US | claimed |
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | claimed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | claimed |
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | claimed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | claimed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | claimed |
| JP-62161769-A | — | — | None | — | — | JP | disclosed |
| US-6906078-B2 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | PHARMACIA CORPORATION (US) | 2005-06-14 | — | — | US | disclosed |
| US-20010047038-A1 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | MOORMAN ALAN E (US) | 2001-11-29 | — | — | US | disclosed |
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |
| EP-0338346-B1 | Quinoxaline derivatives and antiulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0337308-B1 | 2-Pyridylmethylthio derivatives and antiulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4933342-A | Quinoxaline derivatives and antiulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0338346-A2 | Quinoxaline derivatives and antiulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-25 | — | — | EP | disclosed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |
| JP-S62161769-A | NOVEL SULFOXIDE COMPOUND AND PRODUCTION THEREOF | NIPPON CHEMIPHAR CO LTD | 1987-07-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047038-A1 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | ATP4A, ATP1A1, ATP1A4 | PDE10A 2112/4885MAPT 4881/4885MEN1 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.