Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474241 | 0.85 | PDE10A (0.42) | NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9693697 | 0.82 | HPGD (0.39) | NPC1KDM4ERAB9APDGFRBKDR | |
| SCHEMBL6454112 | 0.74 | METAP2 (0.50) | NPC1KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL9695439 | 0.70 | KDM4E (0.37) | NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6442940 | 0.68 | CYP1A2 (0.37) | NPC1KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL11253725 | 0.67 | MAOA (0.43) | SMN1; SMN2ALDH1A1MAPTKMT2AGRIN1 | |
| Hydrochloric Acid SCHEMBL9756590 | 0.67 | HRH1 (0.42) | SMN1; SMN2ALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL6880565 | 0.67 | CBFB (0.36) | NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9668115 | 0.67 | METAP2 (0.50) | NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11183688 | 0.66 | HRH1 (0.39) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | claimed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | claimed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | claimed |
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |