Benzoquinone

Benzoquinone

SCHEMBL969405

O=C1C=CC(=O)C=C1.c1ccoc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 1/20 0.53
BCHE P06276 1/20 0.53
POLB P06746 1/20 0.53
MAOA P21397 1/20 0.53
ACHE P22303 1/20 0.53
MAOB P27338 1/20 0.53
APEX1 P27695 1/20 0.53
CASP1 P29466 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
MDM2 Q00987 1/20 0.53
DHODH Q02127 1/20 0.53
HSD17B10 Q99714 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Furan SCHEMBL27902429 0.75 MAPK1 (0.47) MAPK1TDP1CA1CA9
Maleic Anhydride SCHEMBL4453246 0.75 MAPK1 (0.47) MAPK1TDP1ALDH1A1HSD17B10CA1
Benzoquinone SCHEMBL5335267 0.73 MAOA (0.80) MAPK1TDP1ALDH1A1BCHEPOLB
Furan SCHEMBL4603105 0.73 GSK3A (0.61) MAPK1TDP1CA1CA9
Furan SCHEMBL419906 0.73
Furan SCHEMBL315 0.73
Benzoquinone SCHEMBL460082 0.73 ALDH1A1 (1.00) MAPK1TDP1ALDH1A1BCHEPOLB
Benzoquinone SCHEMBL10506648 0.73 ALDH1A1 (1.00) MAPK1TDP1ALDH1A1BCHEPOLB
Benzoquinone SCHEMBL5308519 0.73 ALDH1A1 (1.00) MAPK1TDP1ALDH1A1BCHEPOLB
Benzoquinone SCHEMBL18103 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115874201-A Electric synthesis method of furan quinone 南京工业大学 2023-03-31 CN claimed
WO-2023146457-A2 A METHOD AND DEVICE FOR ELECTROCHEMICAL HYDROGENATION OF LIQUID ORGANIC HYDROGEN CARRIERS GHORBANI SHIRAZ HAMID (SE) 2023-08-03 WO disclosed
CN-115874201-A Electric synthesis method of furan quinone 南京工业大学 2023-03-31 CN disclosed
CN-115874201-A Electric synthesis method of furan quinone 南京工业大学 2023-03-31 CN disclosed
CN-115874201-A Electric synthesis method of furan quinone 南京工业大学 2023-03-31 CN disclosed
CN-110381963-A It is related to the immunotherapy method and composition of tryptophan metabolic pathway regulator 朱诺治疗学股份有限公司 2019-10-25 CN disclosed
CN-103167904-B Separate film, separating film element and separation film manufacturing method 东丽株式会社 2016-10-26 CN disclosed
CN-103459003-B Spiral separation membrane element and manufacture method thereof TORAY INDUSTRIES, INC. (JP) 2016-04-06 CN disclosed
CN-103338846-B Separation membrane for water treatment and manufacture method thereof TORAY INDUSTRIES, INC. (JP) 2015-07-29 CN disclosed
US-20140154319-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF CARDIAC DISEASE KWAK TAEHWAN (KR) 2014-06-05 US disclosed
US-20100137422-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME YUNGJIN PHARM. CO., LTD. (KR) 2010-06-03 US disclosed
EP-2137175-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME Mazence Inc. (KR) 2009-12-30 EP disclosed
EP-2094262-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM Mazence Inc. (KR) 2009-09-02 EP disclosed
WO-2009084834-A2 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF CARDIAC DISEASE MAZENCE INC. (KR) 2009-07-09 WO disclosed
WO-2009084835-A2 PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF KIDNEY DISEASES MAZENCE INC. (KR) 2009-07-09 WO disclosed
WO-2008133441-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME MAZENCE INC. (KR) 2008-11-06 WO disclosed
WO-2008066301-A1 ANTICANCER COMPOSITION CONTAINING NAPHTHOQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM MAZENCE INC. (KR) 2008-06-05 WO disclosed
WO-2008066296-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM MAZENCE INC. (KR) 2008-06-05 WO disclosed
US-4225645-A CONTAINING A HEXAALKOXYMETHYL MELAMINE UNIROYAL, INC. (US) 1980-09-30 US disclosed
US-4168163-A TREATING WITH LIQUID CONTAINING COLLOIDAL ALUMINA FUJI PHOTO FILM CO., LTD. (JP) 1979-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140154319-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF CARDIAC DISEASE TNNT2, TNNC1, TNNI3 MAPK1 2114/4885TDP1 866/4885ALDH1A1 842/4885
US-20100137422-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME CYP27A1, CYP46A1, PCSK9 MAPK1 1824/4885TDP1 1435/4885ALDH1A1 863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.