SCHEMBL9694567

SCHEMBL9694567

CC(N)CCn1c(=O)cc[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MPO P05164 4/20 0.33
OPRM1 P35372 1/20 0.33
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
ADRA2A P08913 2/20 0.31
BRD4 O60885 1/20 0.31
TAF1 P21675 1/20 0.31
BRPF1 P55201 1/20 0.31
CREBBP Q92793 1/20 0.31
CECR2 Q9BXF3 1/20 0.31
BRD9 Q9H8M2 1/20 0.31
TPO P07202 3/20 0.30
CYP3A4 P08684 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667079 0.83 ALDH1A1 (0.33) ALDH1A1MPOOPRM1
SCHEMBL4348692 0.80 ADRA1D (0.37) MPOOPRM1ADRA1DADRA1AADRA1B
SCHEMBL2930015 0.77 HASPIN (0.35) ADRA1DADRA1AADRA1BBRD4TAF1
SCHEMBL9118472 0.77 KDM4E (0.39) ALDH1A1
SCHEMBL28861793 0.75 TSHR (0.43) ALDH1A1CYP3A4
SCHEMBL17371770 0.74 HASPIN (0.43) ADRA1DADRA1AADRA1B
SCHEMBL6864608 0.74 TDP1 (0.44) ALDH1A1
SCHEMBL3235865 0.73 ADRA1D (0.37) ADRA1DADRA1AADRA1BBRD4TAF1
SCHEMBL2983409 0.73 ADRA1D (0.34) ALDH1A1ADRA1DADRA1AADRA1BBRD4
SCHEMBL28299867 0.73 ADRA1D (0.34) ADRA1DADRA1AADRA1BBRD4TAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0203991-B1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS The Lubrizol Corporation (US) 1992-05-27 EP disclosed
EP-0265520-A1 MODIFIED ASPHALT COMPOSITIONS The Lubrizol Corporation (US) 1988-05-04 EP disclosed
US-4734446-A TRANSMISSION FLUIDS, HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1988-03-29 US disclosed
WO-1987006947-A1 MODIFIED ASPHALT COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-11-19 WO disclosed
US-4677146-A Modified asphalt compositions comprising a nitrogen derivative of an esterified copolymer THE LUBRIZOL CORPORATION (US) 1987-06-30 US disclosed
US-4654403-A ADDITIVES IN TRANSMISSION AND HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1987-03-31 US disclosed
EP-0203991-A1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS. LUBRIZOL CORP (US) 1986-12-10 EP disclosed
US-4594378-A Blend of oil soluble homopolymer of non-aromatic mono-olefin and nitrogen-containing ester of a carboxy containing interpolymer THE LUBRIZOL CORPORATION (US) 1986-06-10 US disclosed
WO-1986003221-A1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1986-06-05 WO disclosed
US-3933761-A INTERPOLYMERS THE LUBRIZOL CORPORATION (US) 1976-01-20 US disclosed