Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696028 | 0.89 | EGFR (0.42) | ELANEPRSS1TPSAB1CHRNB2CHRNB4 | |
| SCHEMBL9696962 | 0.85 | RAB9A (0.44) | ESR1ESR2TDP1MEN1KMT2A | |
| SCHEMBL9696979 | 0.85 | ADRB2 (0.46) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL10603961 | 0.85 | EGFR (0.46) | PRSS1TPSAB1TDP1MEN1KMT2A | |
| SCHEMBL9694883 | 0.84 | ALOX15 (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696046 | 0.84 | ALOX15 (0.43) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696544 | 0.84 | ALOX15 (0.43) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696527 | 0.84 | ALOX15 (0.43) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696260 | 0.84 | ESR1 (0.46) | PRSS1TPSAB1ESR1ESR2TDP1 | |
| SCHEMBL9695950 | 0.83 | ELANE (0.49) | ALOX15ADRB2ADRA2ADRD2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |