Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.30 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637089 | 0.75 | TTR (0.42) | LMNACYP2C9HIF1ACYP1A2PTGS2 | |
| SCHEMBL7593765 | 0.72 | LMNA (0.40) | LMNACYP2C9HIF1ACHRM1TBXA2R | |
| SCHEMBL29181466 | 0.72 | LMNA (0.50) | LMNACYP2C9HIF1ACHRM1TBXA2R | |
| SCHEMBL5572703 | 0.69 | TDP1 (0.31) | LMNACYP2C9HIF1ACHRM1TBXA2R | |
| SCHEMBL124763 | 0.67 | TSHR (0.46) | LMNACYP2C9HIF1ACHRM1TBXA2R | |
| SCHEMBL29394151 | 0.67 | TSHR (0.46) | LMNACYP2C9HIF1ACHRM1TBXA2R | |
| SCHEMBL1000705 | 0.67 | KDM4E (0.44) | LMNACYP2C9HIF1ACYP1A2TDP1 | |
| SCHEMBL31086817 | 0.67 | TPMT (0.41) | LMNACYP2C9HIF1ACHRM1TBXA2R | |
| SCHEMBL3831237 | 0.66 | LMNA (0.43) | LMNACYP2C9HIF1ACHRM1TBXA2R | |
| Iopanoic Acid SCHEMBL38976 | 0.66 | LMNA (1.00) | LMNACYP2C9HIF1ACHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093042-A | Site-specific for liver; diagnosis of metastatic cancer | THE UNIVERSITY OF MICHIGAN (US) | 1992-03-03 | — | — | US | disclosed |
| US-4957729-A | CONTRAST | THE UNIVERSITY OF MICHIGAN (US) | 1990-09-18 | — | — | US | disclosed |
| US-4873075-A | SITE-SPECIFIC TO LIVER AND HEPATOCYTE; SCINTIGRAPHY IMAGING | THE UNIVERSITY OF MICHIGAN (US) | 1989-10-10 | — | — | US | disclosed |