Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696955 | 0.92 | MAPT (0.44) | RAB9ANPC1MAPTKMT2AESR1 | |
| SCHEMBL9695990 | 0.88 | RAB9A (0.43) | RAB9ANPC1MAPTKMT2AALDH1A1 | |
| SCHEMBL9696046 | 0.86 | ALOX15 (0.43) | RAB9ANPC1MAPTKMT2AALDH1A1 | |
| SCHEMBL9696544 | 0.86 | ALOX15 (0.43) | RAB9ANPC1MAPTKMT2AALDH1A1 | |
| SCHEMBL9696037 | 0.85 | ALOX15 (0.40) | RAB9ANPC1KMT2AESR1ESR2 | |
| SCHEMBL10603961 | 0.83 | EGFR (0.46) | RAB9ANPC1KMT2AMEN1HPGD | |
| SCHEMBL9696260 | 0.82 | ESR1 (0.46) | RAB9ANPC1MAPTKMT2AESR1 | |
| SCHEMBL9696945 | 0.80 | NPC1 (0.45) | RAB9ANPC1MAPTKMT2AESR1 | |
| SCHEMBL9695986 | 0.80 | MAPT (0.43) | RAB9ANPC1MAPTKMT2AALDH1A1 | |
| SCHEMBL9696527 | 0.79 | ALOX15 (0.43) | RAB9ANPC1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |