Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520208 | 0.84 | KDM4E (0.57) | KDM4ETDP1MAPTMEN1KMT2A | |
| SCHEMBL9753404 | 0.83 | GAA (0.47) | KDM4ETDP1MAPTMEN1KMT2A | |
| SCHEMBL16373734 | 0.82 | PKM (0.57) | MAPTTP53HTTLMNAALDH1A1 | |
| SCHEMBL5461912 | 0.81 | POLB (0.69) | KMT2ATP53HTTPOLB | |
| SCHEMBL21776305 | 0.78 | TP53 (0.47) | KDM4ETDP1MAPTMEN1KMT2A | |
| SCHEMBL27926418 | 0.77 | CYP1A2 (0.68) | KDM4EMAPTMEN1KMT2ATP53 | |
| SCHEMBL10670593 | 0.77 | LMNA (0.66) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL7850067 | 0.77 | RAB9A (0.62) | KDM4ETDP1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28745357 | 0.76 | CYP1A2 (0.66) | KDM4EMAPTMEN1KMT2ATP53 | |
| SCHEMBL28890678 | 0.76 | KDM4E (0.56) | KDM4ETDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149700-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |