Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700639 | 0.88 | ALDH1A1 (0.35) | NAAAEDNRBEDNRA | |
| SCHEMBL9698268 | 0.84 | NAAA (0.31) | NAAAEDNRBEDNRA | |
| SCHEMBL10392875 | 0.77 | VDR (0.31) | NAAA | |
| SCHEMBL9700881 | 0.76 | S1PR2 (0.31) | NAAA | |
| SCHEMBL9699638 | 0.69 | EBP (0.36) | — | |
| Bromide SCHEMBL9718283 | 0.68 | IDO1 (0.37) | — | |
| SCHEMBL10394793 | 0.68 | CYP3A4 (0.32) | — | |
| SCHEMBL9699643 | 0.65 | MEN1 (0.30) | — | |
| SCHEMBL9699540 | 0.65 | — | — | |
| SCHEMBL9813460 | 0.65 | CYP4F2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106991-A | Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1992-04-21 | — | — | US | disclosed |