Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456222 | 0.76 | NPC1 (0.47) | ALDH1A1SMN1; SMN2MAPTALOX12CYP3A4 | |
| SCHEMBL9701670 | 0.76 | LMNA (0.31) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9701664 | 0.76 | LMNA (0.31) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11416478 | 0.74 | HTT (0.54) | ALDH1A1SMN1; SMN2MAPTALOX12CYP3A4 | |
| SCHEMBL11415823 | 0.73 | KDM4E (0.47) | ALDH1A1SMN1; SMN2MAPTALOX12CYP3A4 | |
| SCHEMBL9701957 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9700902 | 0.70 | POLB (0.36) | ALDH1A1SMN1; SMN2MAPTCYP3A4GAA | |
| SCHEMBL11423572 | 0.67 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTALOX12GAA | |
| SCHEMBL11414292 | 0.67 | KDM4E (0.55) | ALDH1A1SMN1; SMN2MAPTALOX12HPGD | |
| SCHEMBL9700700 | 0.67 | GABRA1 (0.51) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114975-A | Insecticides and miticides | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5026730-A | Anilinophenylthioureas, compositions containing them, and the use thereof in pest control | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |