Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701670 | 1.00 | LMNA (0.31) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL9700587 | 0.76 | ALDH1A1 (0.40) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL9700892 | 0.71 | GABRA1 (0.32) | — | |
| SCHEMBL9700902 | 0.68 | POLB (0.36) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL9701957 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL9700700 | 0.65 | GABRA1 (0.51) | — | |
| SCHEMBL5516786 | 0.61 | ALDH1A1 (0.42) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL43388 | 0.61 | ALDH1A1 (0.42) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL1487730 | 0.60 | TSPO (0.41) | LMNAHTTNPSR1MEN1KMT2A | |
| SCHEMBL3725404 | 0.60 | ALDH1A1 (0.42) | HTTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114975-A | Insecticides and miticides | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5026730-A | Anilinophenylthioureas, compositions containing them, and the use thereof in pest control | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |